ASME-Landmark:Pierce-Donachy Ventricular Assist Device


The Pierce-Donachy Ventricular Assist Device was the first extremely smooth, surgically implantable, seam-free pulsatile blood pump to receive widespread clinical use. After its invention in 1977, it was responsible for saving numerous lives. When used as a bridge to transplant, the pump has a success rate greater than 90 percent. There has never been a device-failure-related fatality of any of these patients.

The pump pioneered the application of fluid mechanics principles to blood pump development and the use of segmented polyurethane as the blood contacting material. An interdisciplinary group, including both medical and engineering colleges at Penn State, designed the pump using fundamental engineering principles and problem solving techniques. William S. Pierce and James H. Donachy received US patent #4,222,127 on September 16, 1980. Other contributors include co-developers Gerson Rosenberg, John A. Brighton, Winfred M. Phillips.

Development began in the early 1970s and testing began in 1973. US Food and Drug Administration approval was granted in 1980, and by 1984, the Penn State heart-assist pump was in widespread use. Today, design principles developed for this pump are being applied to more advanced devices, but the heart assist device is still manufactured and has been implanted in thousands of patients around the world with enhancements including a smaller power unit that allows more patient mobility—including the opportunity to go home while awaiting their heart transplant. See ASME website for more information